SCHEMBL29953466

SCHEMBL29953466

COc1ccc(B(O)O)c(OC(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ENPP2 Q13822 3/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 3/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17157371 1.00 CA1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL3139123 0.89 GPR3 (0.42) NPC1RAB9AALDH1A1TSHRCYP3A4
SCHEMBL4048673 0.86 ENPP2 (0.44) CA1CA2CA12CA7CA9
SCHEMBL29956187 0.86 ENPP2 (0.44) CA1CA2CA12CA7CA9
SCHEMBL263475 0.86 TUBB4A (0.43) CA1CA2CA12CA7CA9
SCHEMBL29956388 0.82 L3MBTL1 (0.44) NPC1ALDH1A1TSHRCYP3A4CYP1A1
SCHEMBL203357 0.81 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL29496939 0.81 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL31522728 0.79 GPR3 (0.37) ENPP2MAPTCRHR1
SCHEMBL22684147 0.79 MAOB (0.38) ENPP2ALDH1A1CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed