Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955932 | 0.89 | KDM4E (0.52) | ALDH1A1GAAKDM4EPOLBMEN1 | |
| SCHEMBL6826964 | 0.74 | KDM4E (0.50) | ALDH1A1GAAEGFRKDM4EPOLB | |
| SCHEMBL16534866 | 0.73 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EPOLBHSD17B10 | |
| SCHEMBL8413824 | 0.72 | KDM4E (0.74) | ALDH1A1GAAKDM4EPOLBHSD17B10 | |
| SCHEMBL29956807 | 0.71 | HTR6 (0.46) | ALDH1A1KDM4EPOLBHSD17B10MEN1 | |
| SCHEMBL12793245 | 0.70 | POLB (0.88) | ALDH1A1GAAKDM4EPOLBHSD17B10 | |
| SCHEMBL847277 | 0.70 | POLB (0.69) | ALDH1A1GAAKDM4EPOLBHSD17B10 | |
| SCHEMBL20380034 | 0.69 | MEN1 (0.61) | ALDH1A1GAAKDM4EPOLBHSD17B10 | |
| SCHEMBL22898794 | 0.69 | LMNA (0.51) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL29363428 | 0.69 | LMNA (0.51) | ALDH1A1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |