Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953765 | 0.89 | ALDH1A1 (0.62) | KDM4EGAAPOLBALDH1A1MEN1 | |
| SCHEMBL12793375 | 0.75 | ALDH1A1 (0.43) | KDM4EGAAATMALPLL3MBTL1 | |
| SCHEMBL29956807 | 0.74 | HTR6 (0.46) | KDM4EPOLBVCAM1ALDH1A1MEN1 | |
| SCHEMBL22898794 | 0.72 | LMNA (0.51) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL29363428 | 0.72 | LMNA (0.51) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL6826652 | 0.72 | ABCB1 (0.54) | KDM4EGAAATMPOLBVCAM1 | |
| SCHEMBL4716108 | 0.72 | NPBWR1 (0.67) | KDM4EGAAPOLBVCAM1NPBWR1 | |
| SCHEMBL14227020 | 0.71 | ALDH1A1 (0.65) | KDM4EGAAATMPOLBALPL | |
| SCHEMBL494192 | 0.70 | KDM4E (0.74) | KDM4EPOLBVCAM1NPBWR1MCHR1 | |
| SCHEMBL24522294 | 0.69 | KDM4E (0.46) | KDM4EGAAPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |