Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061909 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL29958034 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL377917 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL974694 | 0.82 | PKM (0.51) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL6558620 | 0.81 | RORC (0.49) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12511362 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL7055271 | 0.81 | MEN1 (0.50) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL29990241 | 0.79 | POLB (0.68) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL2336203 | 0.79 | POLB (0.68) | ALDH1A1TDP1SMN1; SMN2CA12CA1 | |
| SCHEMBL1527112 | 0.79 | PKM (0.56) | ALDH1A1TDP1SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |