SCHEMBL974694

SCHEMBL974694

CC(=O)Nc1ccc(O)c(C=O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
MEN1 O00255 3/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 1/20 0.50
BRD4 O60885 1/20 0.50
NR1I2 O75469 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MB P02144 1/20 0.50
CYP1A1 P04798 1/20 0.50
CA3 P07451 1/20 0.50
CYP3A4 P08684 1/20 0.50
RARG P13631 1/20 0.50
TSHR P16473 1/20 0.50
ALOX5AP P20292 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527112 0.86 PKM (0.56) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL23225814 0.84 PKM (0.50) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL6069339 0.84 ERN1 (0.49) MEN1MAPTKMT2AALDH1A1POLB
SCHEMBL2560943 0.83 ERN1 (0.59) MEN1KMT2AALDH1A1CYP1A2ERN1
SCHEMBL17867196 0.83 CYP3A4 (0.46) MEN1MAPTKMT2AALDH1A1CA12
SCHEMBL10061909 0.82 ALDH1A1 (0.50) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL29953794 0.82 ALDH1A1 (0.50) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL3231550 0.81 CYP3A4 (0.53) MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL12511362 0.81 ALDH1A1 (0.50) MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL6558620 0.81 RORC (0.49) MEN1MAPTKMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5786520-A CATALYTIC VAPOR PHASE REACTION OF PHENOL COMPOUND WITH AN ALCOHOL RHONE-POULENC CHIMIE (FR) 1998-07-28 US claimed
EP-0599688-B1 Process for O-alkylation of phenolic compounds RHONE POULENC CHIMIE (FR) 1997-08-27 EP claimed
EP-4703358-A1 BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF China Pharmaceutical University (CN) 2026-03-04 EP disclosed
US-20250034091-A1 Small molecule inhibitors of lanosterol synthase BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-01-30 US disclosed
CN-119136798-A Small molecule lanosterol synthase inhibitors 德克萨斯州立大学董事会 2024-12-13 CN disclosed
CN-111655665-B Nitroolefin non-steroidal anti-inflammatory drugs (NA-NSAIDS) and methods of treating inflammation-related disorders 蒙得维的亚巴斯德研究所 2024-11-15 CN disclosed
WO-2024222918-A1 BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF 中国药科大学 2024-10-31 WO disclosed
EP-3732162-B1 NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS INST PASTEUR DE MONTEVIDEO (UY) 2024-03-06 EP disclosed
WO-2023192782-A2 SMALL MOLECULE INHIBITORS OF LANOSTEROL SYNTHASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-10-05 WO disclosed
US-20210107860-A1 NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS INSTITUT PASTEUR DE MONTEVIDEO (UY) 2021-04-15 US disclosed
US-20210107860-A1 NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS INSTITUT PASTEUR DE MONTEVIDEO (UY) 2021-04-15 US disclosed
CN-1668595-A Method for forming carbon-carbon or carbon-heteroatom bonds RHONE POULENC CHIMIE (FR) 2005-09-14 CN disclosed
CN-1217907-C Method for preparing p-hydroxymandelic compounds optically substituted PHODIA CHIMIE (FR) 2005-09-07 CN disclosed
CN-1615284-A Method for forming carbon-carbon bond or carbon-heteroatom bond RHODIA CHIMIE SA (FR) 2005-05-11 CN disclosed
US-20050065350-A1 Method for forming a carbon-carbon or carbon-heteroatom linkage SHASUN PHARMA SOLUTIONS, INC. 2005-03-24 US disclosed
US-6753441-B1 CONDENSING, IN WATER AND BASE, HYDROXYLATED AROMATIC COMPOUND WITH GLYOXYLIC ACID USING POLYCARBOXYLIC ACID CATALYST RHODIA CHIMIE (FR) 2004-06-22 US disclosed
US-20030236413-A1 Catalysis in presence of a metallic element, an imine ligand and nitrogen compound as chelating compound, forming a chemical intermediates in the agrochemical and pharmaceutical fields SHASUN PHARMA SOLUTIONS, INC. 2003-12-25 US disclosed
US-20030171593-A1 Process for arylating or vinylating or alkynating a nucleophilic compound SHASUN PHARMA SOLUTIONS, INC. 2003-09-11 US disclosed
CN-1320111-A Method for preparing p-hydroxymandelic compounds optically substituted PHODIA CHIMIE (FR) 2001-10-31 CN disclosed
US-5786520-A CATALYTIC VAPOR PHASE REACTION OF PHENOL COMPOUND WITH AN ALCOHOL RHONE-POULENC CHIMIE (FR) 1998-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065350-A1 Method for forming a carbon-carbon or carbon-heteroatom linkage COX6C, CBR3, CBR1 PKM 1098/4885MEN1 4353/4885MAPT 3391/4885
US-20030236413-A1 Catalysis in presence of a metallic element, an imine ligand and nitrogen compound as chelating compound, forming a chemical intermediates in the agrochemical and pharmaceutical fields ALK, INMT, ACHE PKM 1333/4885MEN1 615/4885MAPT 3435/4885
US-20250034091-A1 Small molecule inhibitors of lanosterol synthase LSS, CYP51A1, CYP27A1 PKM 3941/4885MEN1 2088/4885MAPT 182/4885
US-20210107860-A1 NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS PTGES, PTGS1, PTGIS PKM 4053/4885MEN1 4684/4885MAPT 2965/4885
US-20030171593-A1 Process for arylating or vinylating or alkynating a nucleophilic compound ALK, ALKBH3, NNMT PKM 1946/4885MEN1 3899/4885MAPT 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.