Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496860 | 1.00 | NPC1 (0.60) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL27765162 | 0.98 | NPC1 (0.58) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL8528387 | 0.95 | NPC1 (0.55) | NPC1MAPTRAB9AMEN1KMT2A | |
| Quinoline SCHEMBL28319703 | 0.95 | ALDH1A1 (0.59) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29267397 | 0.86 | NPC1 (0.48) | NPC1MAPTRAB9AMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL7576455 | 0.85 | CYP3A4 (0.47) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29955934 | 0.85 | ALDH1A1 (0.53) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL401692 | 0.85 | ALDH1A1 (0.53) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29984850 | 0.84 | NPC1 (0.44) | NPC1MAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27466069 | 0.83 | ALDH1A1 (0.52) | NPC1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | claimed |
| EP-3757096-B1 | REDOXINDICATORS FOR A USE IN CELL VIABILITY TESTING | ROCHE DIAGNOSTICS GMBH (DE) | 2025-03-12 | — | — | EP | disclosed |
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4126860-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |