Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL15093758 | 0.88 | CYP3A4 (0.46) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| SCHEMBL496860 | 0.85 | NPC1 (0.60) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| SCHEMBL29953906 | 0.85 | NPC1 (0.60) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| SCHEMBL27765162 | 0.83 | NPC1 (0.58) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| SCHEMBL8528387 | 0.81 | NPC1 (0.55) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| Quinoline SCHEMBL28319703 | 0.81 | ALDH1A1 (0.59) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| Quinoline SCHEMBL5260404 | 0.79 | ALDH1A1 (0.61) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| Quinoline SCHEMBL28462226 | 0.77 | ALDH1A1 (0.59) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| Quinoline SCHEMBL28462227 | 0.77 | ALDH1A1 (0.59) | CYP3A4NPC1MAPTRAB9AMEN1 | |
| SCHEMBL29267397 | 0.73 | NPC1 (0.48) | CYP3A4NPC1MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1139988-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2002-09-25 | — | — | EP | disclosed |
| EP-1139988-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038633-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-07-06 | — | — | WO | disclosed |