Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953906 | 0.95 | NPC1 (0.60) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL496860 | 0.95 | NPC1 (0.60) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL27765162 | 0.93 | NPC1 (0.58) | NPC1MAPTRAB9AMEN1KMT2A | |
| Quinoline SCHEMBL28319703 | 0.90 | ALDH1A1 (0.59) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29267397 | 0.85 | NPC1 (0.48) | NPC1MAPTRAB9AMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL7576455 | 0.81 | CYP3A4 (0.47) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29955934 | 0.80 | ALDH1A1 (0.53) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL28065831 | 0.80 | NPC1 (0.60) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL401692 | 0.80 | ALDH1A1 (0.53) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29984850 | 0.79 | NPC1 (0.44) | NPC1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |