Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496860 | 0.86 | NPC1 (0.60) | NPC1RAB9AMAPTATMMEN1 | |
| SCHEMBL29953906 | 0.86 | NPC1 (0.60) | NPC1RAB9AMAPTATMMEN1 | |
| SCHEMBL8528387 | 0.85 | NPC1 (0.55) | NPC1RAB9AMAPTATMMEN1 | |
| SCHEMBL27765162 | 0.85 | NPC1 (0.58) | NPC1RAB9AMAPTATMMEN1 | |
| Quinoline SCHEMBL28319703 | 0.82 | ALDH1A1 (0.59) | NPC1RAB9AMAPTATMMEN1 | |
| SCHEMBL4037328 | 0.79 | ERN1 (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL196509 | 0.76 | LMNA (0.64) | NPC1RAB9AMAPTMEN1KMT2A | |
| Water SCHEMBL28285432 | 0.74 | LMNA (0.61) | NPC1RAB9AMAPTMEN1KMT2A | |
| 8-Aminoquinoline SCHEMBL2909622 | 0.73 | ERN1 (0.42) | NPC1RAB9AMAPTATMMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7576455 | 0.73 | CYP3A4 (0.47) | NPC1RAB9AMAPTATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114618495-B | Multistage pore carbon-loaded nitrogen-sulfur co-coordinated cobalt monoatomic catalyst and preparation method and application thereof | 中南大学 | 2023-10-20 | — | — | CN | disclosed |