SCHEMBL401692

SCHEMBL401692

O=Cc1ccc2cccnc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
HTT P42858 1/20 0.53
NR4A2 P43354 1/20 0.53
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CASP3 P42574 1/20 0.44
ATM Q13315 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
CYP2A6 P11509 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955934 1.00 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ACASP1CASP7
Hydrochloric Acid SCHEMBL27466069 0.98 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ACASP1CASP7
8-Aminoquinoline SCHEMBL2909622 0.85 ERN1 (0.42) ALDH1A1MEN1KMT2ACASP1CASP7
SCHEMBL29953906 0.85 NPC1 (0.60) ALDH1A1MEN1KMT2ACASP1HTT
SCHEMBL496860 0.85 NPC1 (0.60) ALDH1A1MEN1KMT2ACASP1HTT
Quinoline SCHEMBL28319703 0.84 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ACASP1HTT
SCHEMBL27765162 0.83 NPC1 (0.58) ALDH1A1MEN1KMT2ACASP1HTT
SCHEMBL5620728 0.82 HTT (0.60) ALDH1A1MEN1KMT2ACASP1CASP7
SCHEMBL6651332 0.82 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACASP1CASP7
SCHEMBL6651334 0.82 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113164458-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-13 CN claimed
CN-113164458-A Monoacylglycerol lipase modulators 詹森药业有限公司 2021-07-23 CN claimed
CN-110049985-A HETEROCYCLIC SULFONES AS ROR GAMMA MODULATORS 百时美施贵宝公司 2019-07-23 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-101137655-A Androgen receptor modulator compounds and methods LIGAND PHARM INC (US) 2008-03-05 CN claimed
CN-1245977-C Liposomal antineoplastic drugs and uses thereof INEX PHARMACEUTICALS CORP (CA) 2006-03-22 CN claimed
CN-1391576-A Androgen receptor modulator compounds and methods LIGAND PHARM INC (US) 2003-01-15 CN claimed
CN-1044242-C Heterocyclic-cyclic amine derivatives PFIZER (US) 1999-07-21 CN claimed
CN-1065267-A HETEROCYCLIC-CYCLIC AMINE DERIVATIVES PFIZER (US) 1992-10-14 CN claimed
US-4778802-A PSYCHOTROPIC ACTIVITY; ANTIDEPRESSANTS JOHN WYETH & BROTHER, LTD. (GB) 1988-10-18 US claimed
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
US-12486251-B2 CBP/EP300 inhibitor and use thereof PHARMABLOCK SCIENCES (NANJING) , INC. (CN) 2025-12-02 US disclosed
US-20250325678-A1 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN (CBP) AND/OR ADENOVIRAL E1A BINDING PROTEIN OF 300 KDA (P300) DEGRADATION COMPOUNDS AND METHODS OF USE CULLGEN SHANGHAI INC (CN) 2025-10-23 US disclosed
EP-4573086-A1 METHANOGEN INHIBITORS Agrizeronz Limited Partnership (NZ) 2025-06-25 EP disclosed
CN-1065267-A HETEROCYCLIC-CYCLIC AMINE DERIVATIVES PFIZER (US) 1992-10-14 CN disclosed
WO-1992016104-A1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1992-10-01 WO disclosed
CN-1042912-A (1H-oxazol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives JANSSEN PHARMACEUTICA NV (BE) 1990-06-13 CN disclosed
EP-0371564-A2 (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-06-06 EP disclosed
US-4344956-A Oxotetrahydrothiophenes ERCOLI NICOLO 1982-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325678-A1 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN (CBP) AND/OR ADENOVIRAL E1A BINDING PROTEIN OF 300 KDA (P300) DEGRADATION COMPOUNDS AND METHODS OF USE CREBBP, EP300, CREB1 ALDH1A1 4417/4885MEN1 3103/4885KMT2A 2044/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885MEN1 722/4885KMT2A 3227/4885
US-12486251-B2 CBP/EP300 inhibitor and use thereof EP300, CREBBP, BPTF ALDH1A1 2314/4885MEN1 2211/4885KMT2A 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.