Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952009 | 0.88 | MAPT (0.37) | MTNR1AMTNR1BPPARGPPARAMAPT | |
| SCHEMBL29956515 | 0.81 | TRPV1 (0.43) | MTNR1AMTNR1B | |
| SCHEMBL29951536 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL31247999 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL29954109 | 0.76 | UGT2B7 (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL29957321 | 0.74 | NPC1 (0.37) | PPARGPPARAMAPTTSHRMEN1 | |
| SCHEMBL16061157 | 0.73 | CYP1A2 (0.43) | MEN1KMT2A | |
| SCHEMBL22703183 | 0.72 | ALOX5 (0.59) | CYP3A4MRGPRX4CYP2C19 | |
| SCHEMBL12646813 | 0.72 | CYP1A2 (0.52) | PPARGPPARAMAPTTSHRMEN1 | |
| SCHEMBL25411980 | 0.71 | LMNA (0.43) | MAPTTSHRMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |