Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023976 | 0.80 | ERN1 (0.36) | MPLKDM4EGAAALDH1A1TDP1 | |
| SCHEMBL31437514 | 0.79 | ERN1 (0.38) | KDM4EGAAPTGES2ALDH1A1TDP1 | |
| SCHEMBL19470537 | 0.79 | MEN1 (0.55) | KDM4EGAAALDH1A1TDP1MEN1 | |
| SCHEMBL14354200 | 0.79 | MAOA (0.43) | KDM4EGAAPTGES2ALDH1A1SLC40A1 | |
| SCHEMBL2203041 | 0.76 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29951648 | 0.75 | ALDH1A1 (0.40) | MPLKDM4EGAAPTGES2ALDH1A1 | |
| SCHEMBL2848722 | 0.75 | MPL (0.41) | MPLKDM4EGAAALDH1A1TDP1 | |
| SCHEMBL6535972 | 0.75 | FFAR4 (0.43) | KDM4EALDH1A1MEN1KMT2ASCN9A | |
| SCHEMBL112134 | 0.74 | ALDH1A1 (0.50) | MPLKDM4EGAAALDH1A1TDP1 | |
| SCHEMBL29893374 | 0.74 | ALDH1A1 (0.50) | MPLKDM4EGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |