Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170690 | 0.85 | ERN1 (0.55) | ALDH1A1TDP1ERN1TLR2TLR1 | |
| SCHEMBL27685686 | 0.81 | ERN1 (0.52) | ALDH1A1ERN1TLR2TLR1TLR6 | |
| Bromomethane SCHEMBL28079811 | 0.81 | ERN1 (0.52) | ALDH1A1ERN1TLR2TLR1TLR6 | |
| SCHEMBL11357512 | 0.80 | ALDH1A1 (0.54) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL18414241 | 0.80 | ALDH1A1 (0.54) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL6899284 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TDP1LMNAKDM4EMEN1 | |
| SCHEMBL1028678 | 0.78 | ERN1 (0.63) | ALDH1A1TDP1ERN1TLR2TLR1 | |
| SCHEMBL953118 | 0.78 | ERN1 (0.48) | ALDH1A1ERN1TLR2TLR1TLR6 | |
| SCHEMBL13606236 | 0.77 | ALDH1A1 (0.33) | ALDH1A1ADRA2BPTGS1TDP1ERN1 | |
| SCHEMBL305745 | 0.76 | ERN1 (0.47) | ALDH1A1TDP1ERN1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179052-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-05 | — | — | US | disclosed |
| EP-4486735-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| CN-118786122-A | Herbicidal compounds based on pyrimidinyl-oxy-quinolines | 先正达农作物保护股份公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117551057-A | Benzo ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| US-20240032541-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-02-01 | — | — | US | disclosed |
| WO-2023165874-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| EP-4210489-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2023-07-19 | — | — | EP | disclosed |
| CN-113620875-B | 3-nitrile quinoline derivative and preparation method thereof | 郑州大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116018341-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2023-04-25 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-0497910-A4 | CAMPTOTHECIN ANALOGS AS POTENT INHIBITORS OF HUMAN COLORECTAL CANCER | — | 1992-10-21 | — | — | EP | disclosed |
| EP-0497910-A1 | CAMPTOTHECIN ANALOGS AS POTENT INHIBITORS OF HUMAN COLORECTAL CANCER | RESEARCH TRIANGLE INSTITUTE (US) | 1992-08-12 | — | — | EP | disclosed |
| US-5122526-A | Toposomerase inhibitors; antitumor agents | RESEARCH TRIANGLE INSTITUTE (US) | 1992-06-16 | — | — | US | disclosed |
| US-5106742-A | Camptothecin analogs as potent inhibitors of topoisomerase I | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1992-04-21 | — | — | US | disclosed |
| EP-0436653-A4 | SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF | — | 1992-01-15 | — | — | EP | disclosed |
| EP-0436653-A1 | SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF | RESEARCH TRIANGLE INSTITUTE (US) | 1991-07-17 | — | — | EP | disclosed |
| WO-1991005556-A1 | CAMPTOTHECIN ANALOGS AS POTENT INHIBITORS OF HUMAN COLORECTAL CANCER | RESEARCH TRIANGLE INSTITUTE (US) | 1991-05-02 | — | — | WO | disclosed |
| US-4981968-A | ENZYME INHIBITORS, ANTITUMOR | RESEARCH TRIANGLE INSTITUTE (US) | 1991-01-01 | — | — | US | disclosed |
| WO-1990003169-A1 | SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF | RESEARCH TRIANGLE INSTITUTE (US) | 1990-04-05 | — | — | WO | disclosed |
| US-4894456-A | CYCLIZATION, ESTERIFICATION | RESEARCH TRIANGLE INSTITUTE (US) | 1990-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240032541-A1 | HERBICIDAL COMPOUNDS | HAX1, DDT, MTX1 | ALDH1A1 264/4885ADRA2B 1854/4885PTGS1 1781/4885 |
| US-20250179052-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | PRXL2A, QDPR, PRDX1 | ALDH1A1 351/4885ADRA2B 1309/4885PTGS1 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.