Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APEH | P13798 | 1/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952669 | 0.76 | ENPP2 (0.35) | PPME1HTR6APEHRAPGEF4 | |
| SCHEMBL27662268 | 0.73 | PPME1 (0.49) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL17900455 | 0.73 | PPME1 (0.49) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL28139909 | 0.72 | PPME1 (0.51) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL1599343 | 0.72 | HTR6 (0.50) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL28189646 | 0.72 | HTR6 (0.50) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL1599348 | 0.72 | HTR6 (0.50) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL14760380 | 0.72 | HTR6 (0.50) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL12598891 | 0.71 | HTR6 (0.55) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL29713729 | 0.71 | PPME1 (0.55) | PPME1HTR6LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |