Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956312 | 0.77 | HRH3 (0.37) | CYP2D6CHRM1 | |
| SCHEMBL29952348 | 0.77 | OPRD1 (0.35) | OPRD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL29955064 | 0.74 | ALDH1A1 (0.37) | CA2MEN1KMT2ACA12CA1 | |
| SCHEMBL29957200 | 0.70 | CHRM2 (0.44) | SIGMAR1CHRM2CHRM1 | |
| SCHEMBL8809418 | 0.69 | OPRD1 (0.39) | OPRD1SLC6A4CA2MEN1KMT2A | |
| SCHEMBL27843084 | 0.69 | OPRD1 (0.39) | OPRD1SLC6A4CA2MEN1KMT2A | |
| SCHEMBL931665 | 0.69 | SIGMAR1 (0.43) | OPRD1SLC6A4CA2MEN1KMT2A | |
| SCHEMBL29957972 | 0.69 | OPRD1 (0.43) | OPRD1 | |
| SCHEMBL29954675 | 0.69 | USP2 (0.45) | MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL29956333 | 0.68 | OPRM1 (0.40) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |