Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955064 | 0.78 | ALDH1A1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL29954552 | 0.77 | OPRD1 (0.40) | CYP2D6CHRM1 | |
| SCHEMBL2556650 | 0.75 | L3MBTL1 (0.42) | HRH3ALDH1A1MAPT | |
| SCHEMBL29956333 | 0.75 | OPRM1 (0.40) | ALDH1A1 | |
| SCHEMBL29957200 | 0.74 | CHRM2 (0.44) | HRH3KCNH2KDM4EALDH1A1CHRM1 | |
| SCHEMBL29957972 | 0.73 | OPRD1 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL29954675 | 0.73 | USP2 (0.45) | ALDH1A1MAPTPKMCHRM1 | |
| SCHEMBL23278004 | 0.73 | HRH3 (0.39) | HRH3KCNH2CHRNA7KDM4EALDH1A1 | |
| SCHEMBL2556622 | 0.72 | ALDH1A1 (0.33) | HRH3ALDH1A1 | |
| SCHEMBL3967519 | 0.69 | HRH3 (0.47) | HRH3KCNH2CHRNA7CYP2D6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |