Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330269 | 0.88 | TDP1 (0.42) | TDP1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL15330958 | 0.78 | KMT2A (0.41) | TDP1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL29957675 | 0.70 | SMYD3 (0.40) | TDP1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL29954876 | 0.70 | PKM (0.48) | TDP1KMT2ASMYD3L3MBTL1RAB9A | |
| SCHEMBL29957012 | 0.69 | ITGB3 (0.44) | TDP1KMT2AALDH1A1SMYD3POLB | |
| SCHEMBL8284047 | 0.68 | TDP1 (0.58) | TDP1KMT2AALDH1A1GAASMYD3 | |
| SCHEMBL27483961 | 0.67 | SMYD3 (0.51) | TDP1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL29955250 | 0.66 | SMYD3 (0.47) | TDP1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL15332731 | 0.66 | CA2 (0.47) | TDP1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL29953517 | 0.66 | CA2 (0.47) | TDP1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |