Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957675 | 0.79 | SMYD3 (0.40) | KMT2AHSD17B10SMYD3MEN1POLB | |
| SCHEMBL29953018 | 0.74 | MEN1 (0.52) | KMT2ASMYD3MEN1POLBALDH1A1 | |
| SCHEMBL15330958 | 0.72 | KMT2A (0.41) | KMT2ASMYD3MEN1POLBNPC1 | |
| SCHEMBL29958499 | 0.72 | MAPK1 (0.54) | ITGB3ITGA2BKMT2ASMYD3MEN1 | |
| SCHEMBL15330269 | 0.71 | TDP1 (0.42) | KMT2ASMYD3MEN1POLBNPC1 | |
| SCHEMBL29953684 | 0.71 | SMYD3 (0.51) | KMT2ASMYD3MEN1POLBALDH1A1 | |
| SCHEMBL18912258 | 0.71 | TBXAS1 (0.47) | ITGB3ITGA2BNPC1RAB9AALDH1A1 | |
| SCHEMBL11335716 | 0.70 | HDAC6 (0.52) | KMT2AMEN1 | |
| SCHEMBL27483961 | 0.70 | SMYD3 (0.51) | KMT2ASMYD3MEN1NPC1RAB9A | |
| SCHEMBL29954567 | 0.69 | TDP1 (0.40) | KMT2ASMYD3MEN1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |