Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330958 | 0.86 | KMT2A (0.41) | SMYD3KMT2APKMALDH1A1BRD4 | |
| SCHEMBL29957012 | 0.79 | ITGB3 (0.44) | SMYD3KMT2AALDH1A1POLBMEN1 | |
| SCHEMBL29953684 | 0.72 | SMYD3 (0.51) | SMYD3KMT2AALDH1A1BRD4AKR1C3 | |
| SCHEMBL9039965 | 0.72 | TSHR (0.53) | ALDH1A1ALDH2KDM4E | |
| SCHEMBL29954876 | 0.72 | PKM (0.48) | SMYD3KMT2APKML3MBTL1TDP1 | |
| SCHEMBL18912259 | 0.71 | ALDH1A1 (0.41) | KMT2AALDH1A1ALDH2KDM4ESMN1; SMN2 | |
| SCHEMBL14306186 | 0.71 | RAB9A (0.40) | KMT2AALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL29953585 | 0.71 | ALDH1A1 (0.38) | KMT2AALDH1A1ALDH2BRD4L3MBTL1 | |
| SCHEMBL15330269 | 0.70 | TDP1 (0.42) | SMYD3KMT2AALDH1A1AKR1C3L3MBTL1 | |
| SCHEMBL29953018 | 0.70 | MEN1 (0.52) | SMYD3KMT2AALDH1A1AKR1C3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |