Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2995466

O=C(O)C(F)(F)F.O=C(O)c1cc2c(s1)c(C1CCCCC1)c(-c1ccccc1)n2CCc1cccnc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
TPSAB1 Q15661 1/20 0.37
FABP4 P15090 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
C3AR1 Q16581 4/20 0.34
APAF1 O14727 1/20 0.34
PABPC1 P11940 1/20 0.34
CASP6 P55212 1/20 0.34
CASP8 Q14790 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
CNR2 P34972 1/20 0.33
ATM Q13315 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2995589 0.92 GRIN1 (0.37) TPSAB1F2F10CNR2
SCHEMBL5237385 0.87 KDM4E (0.40) DRD2DRD4CNR2CHRNB2CHRNA7
Trifluoroacetic Acid SCHEMBL2992079 0.82 MEN1 (0.36) FABP4
SCHEMBL27642151 0.81 GRIN1 (0.35) CNR2
Trifluoroacetic Acid SCHEMBL2995465 0.79 DPP4 (0.36) F2ATM
SCHEMBL2998608 0.79 CNR1 (0.37) FABP4CNR2
SCHEMBL13211511 0.79 ALDH1A1 (0.37) FABP4CNR2TBXAS1
SCHEMBL13211491 0.78 TBXAS1 (0.46) TBXAS1
SCHEMBL5229364 0.77 MEN1 (0.40) FABP4
SCHEMBL13211483 0.76 FABP4 (0.38) FABP4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781431-B2 Thienopyrroles as antiviral agents ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) 2010-08-24 US claimed