Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2995589 | 0.95 | GRIN1 (0.37) | KDM4EPOLBCNR2FEN1ALDH1A1 | |
| SCHEMBL2998608 | 0.91 | CNR1 (0.37) | KDM4EPOLBCNR2FEN1ALDH1A1 | |
| SCHEMBL13211511 | 0.90 | ALDH1A1 (0.37) | KDM4EPOLBCNR2FEN1ALDH1A1 | |
| SCHEMBL27642151 | 0.87 | GRIN1 (0.35) | KDM4EPOLBCNR2ALDH1A1TBXA2R | |
| Trifluoroacetic Acid SCHEMBL2995466 | 0.87 | DRD2 (0.38) | CNR2DRD2DRD4CHRNB2CHRNA7 | |
| SCHEMBL13211510 | 0.83 | FEN1 (0.39) | KDM4ECNR2FEN1ALDH1A1MAPT | |
| SCHEMBL13211489 | 0.82 | GABRA1 (0.39) | KDM4ECNR2ALDH1A1 | |
| SCHEMBL27642142 | 0.81 | FABP4 (0.35) | POLBALDH1A1MAPTBLM | |
| SCHEMBL13211483 | 0.81 | FABP4 (0.38) | KDM4EPOLBALDH1A1 | |
| SCHEMBL4864988 | 0.81 | MAPK14 (0.35) | KDM4ECNR2ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |