Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625460 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4TSHRACHE | |
| SCHEMBL29952455 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HSD17B10RAB9AKMT2AKDM4E | |
| SCHEMBL3089372 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HSD17B10RAB9AKMT2AKDM4E | |
| SCHEMBL7053977 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TP53CYP3A4TSHRACHE | |
| SCHEMBL29956524 | 0.71 | ERN1 (0.35) | ALDH1A1KDM4EHPGDLMNACCR1 | |
| SCHEMBL11929836 | 0.71 | KMT2A (0.45) | ALDH1A1CYP3A4RAB9AKMT2AKDM4E | |
| SCHEMBL13724354 | 0.71 | GRM4 (0.53) | CYP3A4TSHRRAB9AMAPT | |
| SCHEMBL21338123 | 0.71 | CCR1 (0.32) | LMNACCR1 | |
| SCHEMBL10167712 | 0.70 | NOS3 (0.43) | ALDH1A1TP53CYP3A4TSHRACHE | |
| SCHEMBL29600243 | 0.70 | NOS2 (0.44) | ALDH1A1TP53HSD17B10RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |