Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 7/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092631 | 0.75 | ENPP2 (0.40) | ENPP2KDM4ECA1CA2CA4 | |
| SCHEMBL12004168 | 0.73 | ALDH1A1 (0.43) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL29956057 | 0.73 | ADRA2A (0.42) | ENPP2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL29958138 | 0.73 | CCR1 (0.48) | NPC1RAB9AKDM4EALDH1A1CA2 | |
| SCHEMBL2210203 | 0.73 | L3MBTL1 (0.45) | ENPP2NPC1RAB9AKMT2ALMNA | |
| SCHEMBL14769188 | 0.73 | ORAI1 (0.37) | RAB9A | |
| SCHEMBL200776 | 0.73 | CCR1 (0.48) | NPC1RAB9AKDM4EALDH1A1CA2 | |
| SCHEMBL29681228 | 0.73 | ORAI1 (0.37) | RAB9A | |
| SCHEMBL28375630 | 0.73 | ADRA2A (0.42) | ENPP2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL29956948 | 0.70 | ENPP2 (0.36) | ENPP2NPC1RAB9AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |