Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200776 | 1.00 | CCR1 (0.48) | CCR1CCR5CCR8HDAC6NOS3 | |
| SCHEMBL1843031 | 0.88 | CCR1 (0.39) | CCR1CCR5CCR8HDAC6NOS3 | |
| SCHEMBL10092631 | 0.73 | ENPP2 (0.40) | CA2LPLLIPGKDM4E | |
| SCHEMBL29954840 | 0.73 | ENPP2 (0.40) | CA2RAB9AMAPTNPC1KDM4E | |
| SCHEMBL8931093 | 0.73 | CCR1 (0.44) | CCR1CCR5CCR8HDAC6NOS3 | |
| SCHEMBL28375630 | 0.71 | ADRA2A (0.42) | CA2RAB9AADRA2AADRA2BADRA2C | |
| SCHEMBL2210203 | 0.71 | L3MBTL1 (0.45) | RAB9AADRA2AADRA2BADRA2CPLAU | |
| SCHEMBL29957065 | 0.71 | NOS3 (0.44) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL29681228 | 0.71 | ORAI1 (0.37) | RAB9AORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL29956057 | 0.71 | ADRA2A (0.42) | CA2RAB9AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678641-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |