Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811087 | 0.75 | KMT2A (0.41) | KMT2APCSK9BRD4ALDH1A1KDM4E | |
| SCHEMBL9273371 | 0.74 | BRD4 (0.46) | KMT2APCSK9BRD4ALDH1A1KDM4E | |
| SCHEMBL29518719 | 0.71 | KMT2A (0.41) | KMT2APCSK9BRD4ALDH1A1KDM4E | |
| SCHEMBL23320081 | 0.70 | KMT2A (0.47) | KMT2AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL10940232 | 0.70 | KMT2A (0.41) | KMT2APCSK9BRD4ALDH1A1GAA | |
| SCHEMBL17279818 | 0.69 | MMP3 (0.54) | KMT2ABRD4ALDH1A1KDM4EGLA | |
| SCHEMBL29955367 | 0.67 | CA2 (0.37) | CA2 | |
| SCHEMBL17266867 | 0.67 | BRD4 (0.52) | KMT2APCSK9BRD4ALDH1A1KDM4E | |
| SCHEMBL10462449 | 0.67 | HPGD (0.45) | BRD4ALDH1A1GAAHPGDCOMT | |
| SCHEMBL1777961 | 0.67 | ALDH1A1 (0.46) | KMT2APCSK9BRD4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |