Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955309 | 0.82 | ALOX15 (0.45) | ALOX15KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL29955788 | 0.81 | NPC1 (0.50) | ALOX15KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL29951232 | 0.80 | CXCR2 (0.47) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29951020 | 0.77 | LMNA (0.49) | ALOX15KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL29955289 | 0.73 | CXCR2 (0.39) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29950832 | 0.72 | ALDH1A1 (0.39) | KMT2AHTTALDH1A1KDM4ENPC1 | |
| SCHEMBL29953114 | 0.72 | LMNA (0.55) | ALOX15KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL29955260 | 0.71 | SMN1; SMN2 (0.47) | ALOX15KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL29956655 | 0.70 | CXCR2 (0.40) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15330335 | 0.70 | HSD17B10 (0.44) | KMT2AHTTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |