Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553177 | 0.88 | TSHR (0.43) | NOTUMRAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL29951452 | 0.87 | RAB9A (0.35) | OPRM1OPRL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2561856 | 0.84 | OPRM1 (0.41) | NOTUMOPRM1OPRL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15331627 | 0.83 | HPGD (0.48) | NPC1ALDH1A1TSHR | |
| SCHEMBL29952087 | 0.82 | TSHR (0.40) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29956046 | 0.81 | MPO (0.38) | RAB9ASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2559106 | 0.81 | MEN1 (0.45) | NOTUMSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29950794 | 0.79 | KMT2A (0.41) | RAB9ASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL19370709 | 0.78 | TDP1 (0.41) | OPRM1OPRL1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29956007 | 0.78 | MAOA (0.49) | OPRM1OPRL1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |