Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350664 | 0.73 | PLAU (0.50) | PLGF12 | |
| SCHEMBL1190802 | 0.73 | PLAU (0.50) | PLGF12 | |
| SCHEMBL29421593 | 0.68 | NOS3 (0.54) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL22589259 | 0.68 | LMNA (0.42) | F12 | |
| SCHEMBL26462746 | 0.64 | PLAU (0.45) | PLGF12 | |
| SCHEMBL22045587 | 0.64 | KDM4E (0.34) | — | |
| SCHEMBL29957870 | 0.64 | ASIC3 (0.37) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL29952483 | 0.64 | HTR2C (0.40) | — | |
| SCHEMBL29952452 | 0.63 | CYP2A6 (0.35) | — | |
| SCHEMBL29957043 | 0.63 | HTR2C (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |