SCHEMBL29956959

SCHEMBL29956959

Cc1cc(N(C)C)ncc1B(O)O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CRHR1 P34998 4/20 0.33
AOC3 Q16853 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
MAP3K11 Q16584 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842549 1.00 CYP1A2 (0.35) CYP1A2ALDH1A1CYP3A4CYP2D6CYP2C19
SCHEMBL12535565 0.76 NOS3 (0.46) CYP1A2ALDH1A1CYP3A4CYP2D6CYP2C19
SCHEMBL5748850 0.76 ENPP2 (0.37) CYP1A2ALDH1A1CYP2C19HSD17B10MEN1
SCHEMBL5747919 0.76 HCAR3 (0.31)
SCHEMBL22445288 0.74 UHRF1 (0.48) CYP1A2
SCHEMBL29951379 0.74 UHRF1 (0.48) CYP1A2
SCHEMBL5768702 0.73 RXRA (0.33) ALDH1A1
SCHEMBL2725352 0.71 CYP3A4 (0.34) CYP3A4CYP2C19
SCHEMBL21262370 0.71 MEN1 (0.41) CYP1A2ALDH1A1CYP3A4CYP2D6CYP2C19
SCHEMBL1459842 0.71 ALDH1A1 (0.36) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed