Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951834 | 0.81 | MAPT (0.39) | MAPTMAPK8HTTADORA1SMN1; SMN2 | |
| SCHEMBL19132575 | 0.80 | MAPT (0.38) | MAPTMAPK8HTTADORA1BTK | |
| SCHEMBL29653296 | 0.79 | NNMT (0.50) | HTTALDH1A1NNMTCYP1A2 | |
| SCHEMBL248283 | 0.79 | NNMT (0.50) | HTTALDH1A1NNMTCYP1A2 | |
| SCHEMBL25447293 | 0.78 | LIPE (0.53) | MAPTHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12903736 | 0.76 | NOS3 (0.41) | MAPTMAPK8HTTADORA1LMNA | |
| SCHEMBL16783076 | 0.73 | BTK (0.37) | MAPTMAPK8HTTADORA1LMNA | |
| SCHEMBL10153938 | 0.73 | MAPT (0.37) | MAPTMAPK8HTTADORA1LMNA | |
| SCHEMBL12113611 | 0.73 | ALDH1A1 (0.41) | MAPTMAPK8HTTADORA1LMNA | |
| SCHEMBL26418873 | 0.72 | GPR88 (0.38) | MAPTMAPK8HTTADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |