Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285122 | 1.00 | MRGPRX4 (0.60) | MRGPRX4MAPTHPGDNPC1LMNA | |
| SCHEMBL30518379 | 0.85 | MAPT (0.58) | MRGPRX4MAPTHPGDNPC1LMNA | |
| SCHEMBL257756 | 0.85 | MAPT (0.58) | MRGPRX4MAPTHPGDNPC1LMNA | |
| SCHEMBL2560724 | 0.82 | GPR84 (0.55) | MRGPRX4MAPTHPGDNPC1LMNA | |
| SCHEMBL2557998 | 0.81 | NPC1 (0.59) | MRGPRX4MAPTHPGDNPC1RAB9A | |
| SCHEMBL2557545 | 0.81 | MRGPRX4 (0.59) | MRGPRX4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27629 | 0.79 | MRGPRX4 (0.67) | MRGPRX4MAPTHPGDNPC1LMNA | |
| SCHEMBL29568609 | 0.79 | MRGPRX4 (0.67) | MRGPRX4MAPTHPGDNPC1LMNA | |
| SCHEMBL2553887 | 0.78 | ENPP2 (0.51) | MRGPRX4MAPTLMNAENPP2ALDH1A1 | |
| SCHEMBL9389089 | 0.78 | LIPE (0.51) | MRGPRX4MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715015-A | Selective PHD1 inhibitor compounds, compositions and methods of use | 阿克比治疗有限公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |