Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.47 |
| ▸ | CFD | P00746 | 2/20 | 0.45 |
| ▸ | F11 | P03951 | 2/20 | 0.45 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331178 | 0.84 | LIPE (0.53) | ENPP2LIPEABCB1HTR1ADRD2 | |
| SCHEMBL2557545 | 0.82 | MRGPRX4 (0.59) | ENPP2LIPEABCB1HTR1AMRGPRX4 | |
| SCHEMBL11919282 | 0.81 | LMNA (0.64) | ABCB1HTR1ADRD2MRGPRX4LMNA | |
| SCHEMBL2557998 | 0.79 | NPC1 (0.59) | ENPP2LIPEMRGPRX4MAPTNPSR1 | |
| SCHEMBL20257761 | 0.79 | SLC1A5 (0.55) | ABCB1HTR1ADRD2MRGPRX4L3MBTL1 | |
| SCHEMBL25285122 | 0.78 | MRGPRX4 (0.60) | ENPP2LIPEMRGPRX4LMNAGAA | |
| SCHEMBL29958263 | 0.78 | MRGPRX4 (0.60) | ENPP2LIPEMRGPRX4LMNAGAA | |
| SCHEMBL2557599 | 0.78 | ENPP2 (0.51) | ENPP2LIPEHTR1AMRGPRX4LPL | |
| SCHEMBL1894256 | 0.78 | HTR1A (0.67) | LIPEABCB1HTR1ADRD2LMNA | |
| SCHEMBL15309966 | 0.78 | CFD (0.61) | ABCB1HTR1ADRD2MRGPRX4CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |