Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899441 | 1.00 | ATM (0.43) | ATMTOP1TOP2AP2RX4CYP1A2 | |
| SCHEMBL2749071 | 0.82 | TOP1 (0.42) | ATMTOP1TOP2AP2RX4MEN1 | |
| SCHEMBL4928476 | 0.81 | HDAC3 (0.39) | CYP1A2CYP2D6MEN1ALDH1A1KMT2A | |
| SCHEMBL9421176 | 0.69 | TOP1 (0.41) | ATMTOP1TOP2AP2RX4CYP1A2 | |
| SCHEMBL8215227 | 0.69 | KEAP1 (0.49) | ATMP2RX4CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL4522727 | 0.69 | MAPK1 (0.43) | ATMTOP1TOP2ACYP1A2CYP2D6 | |
| SCHEMBL10005481 | 0.69 | MAPK1 (0.43) | ATMTOP1TOP2AP2RX4CYP1A2 | |
| SCHEMBL8445731 | 0.68 | TOP1 (0.56) | TOP1TOP2ACYP1A2CYP2D6MEN1 | |
| SCHEMBL14273164 | 0.68 | TOP1 (0.56) | TOP1TOP2ACYP1A2CYP2D6MEN1 | |
| Acetamide SCHEMBL28954498 | 0.68 | ATM (0.54) | ATMP2RX4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624214-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-12595370-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20240067825-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2024-02-29 | — | — | US | disclosed |
| US-20220340760-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595370-B2 | Polymerizable absorbers of UV and high energy visible light | NLRP3, NLRP1, XDH | ATM 31/4885TOP1 1054/4885TOP2A 837/4885 |
| US-12624214-B2 | Polymerizable absorbers of UV and high energy visible light | CRY1, SCNN1G, MALT1 | ATM 270/4885TOP1 660/4885TOP2A 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.