Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112159 | 0.83 | TOP1 (0.36) | MAPK1KDM4EATMMAOAMAOB | |
| SCHEMBL19659080 | 0.80 | MAPK1 (0.36) | MAPK1KDM4EATMCYP1A2CYP2D6 | |
| SCHEMBL15160874 | 0.77 | ALDH1A1 (0.57) | MAOAMAOBCYP1A2CYP2D6TOP1 | |
| SCHEMBL599045 | 0.76 | DRD2 (0.43) | MAPK1KDM4EATMMAOACYP1A2 | |
| SCHEMBL4522727 | 0.76 | MAPK1 (0.43) | MAPK1KDM4EATMMAOAMAOB | |
| SCHEMBL19537981 | 0.73 | MAPK1 (0.61) | MAPK1KDM4EATMMAOAMAOB | |
| SCHEMBL5693983 | 0.73 | MAPK1 (0.61) | MAPK1KDM4EATMMAOAMAOB | |
| SCHEMBL5150290 | 0.73 | STK17B (0.56) | MAPK1KDM4EATMMAOAMAOB | |
| SCHEMBL9421176 | 0.73 | TOP1 (0.41) | MAPK1KDM4EATMMAOAMAOB | |
| SCHEMBL4952565 | 0.73 | MAPK1 (0.41) | MAPK1KDM4EATMMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835655-B2 | Process for preparing olopatadine and/or a pharmaceutically acceptable salt thereof | ZACH SYSTEM S.P.A (IT) | 2014-09-16 | — | — | US | disclosed |
| US-20120016138-A1 | PROCESS FOR PREPARING OLOPATADINE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZACH SYSTEM S.P.A. (IT) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016138-A1 | PROCESS FOR PREPARING OLOPATADINE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | QDPR, OPRD1, O60361 | MAPK1 678/4885KDM4E 1117/4885ATM 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.