SCHEMBL29958563

SCHEMBL29958563

Cc1c(C=O)oc2ccc(OCc3ccccc3)cc12

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.65
PKM P14618 1/20 0.65
CASP3 P42574 2/20 0.58
SENP8 Q96LD8 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58
MAOB P27338 8/20 0.56
ACHE P22303 2/20 0.56
MAOA P21397 6/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
SLC26A4 O43511 3/20 0.47
BLM P54132 1/20 0.47
ATM Q13315 1/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL724161 1.00 L3MBTL1 (0.65) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL24484859 0.82 MAPT (0.63) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL25707033 0.80 KDM4E (0.40) L3MBTL1PKMNPC1RAB9AKMT2A
SCHEMBL5746156 0.79 CASP3 (0.63) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL720239 0.79 CASP3 (0.70) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL719690 0.78 L3MBTL1 (0.60) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL717257 0.78 KDM4E (0.60) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL718464 0.77 L3MBTL1 (0.58) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL9727459 0.77 L3MBTL1 (0.58) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL717397 0.77 CASP3 (0.61) L3MBTL1PKMCASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151541-B Novel compounds and uses thereof 德彪药业国际股份公司 2024-06-25 CN disclosed
EP-4077324-A1 NOVEL COMPOUNDS AND THEIR USE Debiopharm International SA (CH) 2022-10-26 EP disclosed
CN-115151541-A Novel compound and use thereof 德彪药业国际股份公司 2022-10-04 CN disclosed