SCHEMBL724161

SCHEMBL724161

Cc1c(C=O)oc2ccc(OCc3ccccc3)cc12

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.65
PKM P14618 1/20 0.65
CASP3 P42574 2/20 0.58
SENP8 Q96LD8 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58
MAOB P27338 8/20 0.56
ACHE P22303 2/20 0.56
MAOA P21397 6/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
SLC26A4 O43511 3/20 0.47
BLM P54132 1/20 0.47
ATM Q13315 1/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29958563 1.00 L3MBTL1 (0.65) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL24484859 0.82 MAPT (0.63) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL25707033 0.80 KDM4E (0.40) L3MBTL1PKMNPC1RAB9AKMT2A
SCHEMBL5746156 0.79 CASP3 (0.63) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL720239 0.79 CASP3 (0.70) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL719690 0.78 L3MBTL1 (0.60) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL717257 0.78 KDM4E (0.60) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL718464 0.77 L3MBTL1 (0.58) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL9727459 0.77 L3MBTL1 (0.58) L3MBTL1PKMCASP3SENP8SENP7
SCHEMBL717397 0.77 CASP3 (0.61) L3MBTL1PKMCASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473283-B2 Compounds and their use DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-11-18 US disclosed
CN-115151541-B Novel compounds and uses thereof 德彪药业国际股份公司 2024-06-25 CN disclosed
US-20230159519-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2023-05-25 US disclosed
US-20230159519-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2023-05-25 US disclosed
EP-4077324-A1 NOVEL COMPOUNDS AND THEIR USE Debiopharm International SA (CH) 2022-10-26 EP disclosed
CN-115151541-A Novel compound and use thereof 德彪药业国际股份公司 2022-10-04 CN disclosed
WO-2021123372-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2021-06-24 WO disclosed
WO-2021123372-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2021-06-24 WO disclosed
US-8436043-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-05-07 US disclosed
US-20120270865-A2 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-10-25 US disclosed
US-20120053173-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-01 US disclosed
EP-2251326-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2010-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053173-A1 HETEROCYCLIC COMPOUND SLC5A2, SLC5A1, IAPP L3MBTL1 4088/4885PKM 2662/4885CASP3 489/4885
US-20230159519-A1 NOVEL COMPOUNDS AND THEIR USE LSS, PGLS, LDHB L3MBTL1 191/4885PKM 1498/4885CASP3 1157/4885
US-20120270865-A2 HETEROCYCLIC COMPOUND SLC5A2, SLC5A1, IAPP L3MBTL1 4088/4885PKM 2662/4885CASP3 489/4885
US-12473283-B2 Compounds and their use LSS, PGLS, LDHB L3MBTL1 125/4885PKM 1167/4885CASP3 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.