Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 3/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23532065 | 0.83 | L3MBTL1 (0.57) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL719690 | 0.83 | L3MBTL1 (0.60) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL9739761 | 0.81 | ALOX5 (0.59) | NPC1RAB9AMEN1KMT2AALOX5 | |
| SCHEMBL3399151 | 0.81 | L3MBTL1 (0.57) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL724161 | 0.77 | L3MBTL1 (0.65) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL29958563 | 0.77 | L3MBTL1 (0.65) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL718464 | 0.74 | L3MBTL1 (0.58) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL720239 | 0.73 | CASP3 (0.70) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL9740626 | 0.73 | ALOX5 (0.45) | MEN1KMT2AMAOBALOX5KDM4E | |
| SCHEMBL26693543 | 0.73 | CASP3 (0.66) | L3MBTL1PKMCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |