Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958355 | 0.72 | — | — | |
| SCHEMBL30705391 | 0.63 | TAS2R14 (0.40) | — | |
| SCHEMBL14596841 | 0.58 | ALOX15 (0.42) | — | |
| SCHEMBL11065049 | 0.58 | DRD1 (0.56) | — | |
| SCHEMBL12817707 | 0.58 | POLB (0.42) | — | |
| SCHEMBL2211626 | 0.57 | DRD1 (0.47) | — | |
| SCHEMBL9874298 | 0.56 | KCNN4 (0.36) | — | |
| SCHEMBL6257916 | 0.56 | — | — | |
| SCHEMBL28211992 | 0.56 | FAAH (0.42) | — | |
| SCHEMBL23678581 | 0.56 | DRD1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308122-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-01-24 | — | — | EP | disclosed |
| CN-116981459-A | Heterocyclic derivatives as janus kinase inhibitors | 奇斯药制品公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022194779-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-09-22 | — | — | WO | disclosed |