Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | GRK2 | P25098 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723775 | 0.89 | BCHE (0.53) | BCHEPLOD2PLOD3PLOD1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL27535061 | 0.79 | FFAR1 (0.50) | L3MBTL1FFAR1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL15778253 | 0.79 | ROCK2 (0.49) | BCHEGRK2ROCK2FFAR1 | |
| SCHEMBL951015 | 0.77 | FFAR1 (0.58) | L3MBTL1FFAR1MEN1KMT2ALMNA | |
| SCHEMBL11481061 | 0.75 | MDM2 (0.52) | BCHEL3MBTL1GRK2ROCK2MDM2 | |
| SCHEMBL5692310 | 0.74 | ALDH1A1 (0.44) | FFAR1MEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL4535893 | 0.74 | PORCN (0.57) | GRK2ROCK2MEN1KMT2ALMNA | |
| SCHEMBL3197308 | 0.74 | BCHE (0.59) | BCHEL3MBTL1MDM2TAAR1FFAR1 | |
| Trifluoroacetic Acid SCHEMBL28175119 | 0.74 | ALDH1A1 (0.45) | BCHEPLOD2PLOD3PLOD1L3MBTL1 | |
| SCHEMBL5167269 | 0.72 | MDM2 (0.48) | BCHEL3MBTL1GRK2ROCK2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308122-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022194779-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-09-22 | — | — | WO | disclosed |