Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 4/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240298 | 1.00 | LMNA (0.55) | LMNAKMT2AGAAALDH1A1CYP1A2 | |
| SCHEMBL29960482 | 0.88 | L3MBTL1 (0.49) | LMNAKMT2AALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL3123358 | 0.85 | NPSR1 (0.52) | LMNAKMT2AGAAALDH1A1CYP1A2 | |
| SCHEMBL20240279 | 0.84 | LMNA (0.67) | LMNAKMT2AGAAALDH1A1CYP1A2 | |
| SCHEMBL3129398 | 0.84 | LMNA (0.65) | LMNAKMT2AGAAALDH1A1CYP1A2 | |
| SCHEMBL3507291 | 0.80 | USP2 (0.61) | KMT2AGAAALDH1A1L3MBTL1TP53 | |
| SCHEMBL27489857 | 0.80 | L3MBTL1 (0.59) | LMNAKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2436534 | 0.80 | L3MBTL1 (0.65) | KMT2AALDH1A1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL8393465 | 0.79 | LMNA (0.73) | LMNAKMT2AGAAALDH1A1CYP1A2 | |
| SCHEMBL521860 | 0.79 | AKR1C3 (0.68) | LMNAKMT2AALDH1A1L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |