Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240298 | 0.88 | LMNA (0.55) | L3MBTL1TP53SMN1; SMN2USP2TSHR | |
| SCHEMBL29960461 | 0.88 | LMNA (0.55) | L3MBTL1TP53SMN1; SMN2USP2TSHR | |
| SCHEMBL29960804 | 0.85 | AKR1C3 (0.61) | LMNARAB9ANPC1KMT2AHTT | |
| SCHEMBL29960046 | 0.83 | LMNA (0.48) | SMN1; SMN2LMNANPC1KMT2AHTT | |
| SCHEMBL27489857 | 0.79 | L3MBTL1 (0.59) | L3MBTL1TP53SMN1; SMN2USP2TSHR | |
| SCHEMBL3507291 | 0.79 | USP2 (0.61) | L3MBTL1TP53SMN1; SMN2USP2TSHR | |
| SCHEMBL2436534 | 0.79 | L3MBTL1 (0.65) | L3MBTL1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL29960686 | 0.78 | HDAC8 (0.40) | SMN1; SMN2LMNARAB9ANPC1KMT2A | |
| SCHEMBL521860 | 0.78 | AKR1C3 (0.68) | L3MBTL1TP53SMN1; SMN2TSHRLMNA | |
| SCHEMBL18610115 | 0.77 | POLB (0.54) | L3MBTL1TP53SMN1; SMN2USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |