Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GCK | P35557 | 5/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960482 | 0.78 | L3MBTL1 (0.49) | MAPTPYGMLMNANPC1RAB9A | |
| SCHEMBL29960529 | 0.77 | ALDH1A1 (0.55) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL29960804 | 0.77 | AKR1C3 (0.61) | HDAC8LMNANPC1RAB9AGAA | |
| SCHEMBL29960046 | 0.76 | LMNA (0.48) | HDAC8GCKPYGMLMNANPC1 | |
| SCHEMBL28010661 | 0.72 | POLB (0.67) | HDAC8MAPTLMNANPC1RAB9A | |
| SCHEMBL141456 | 0.69 | ELANE (0.57) | MAPTLMNAELANEKMT2AALDH1A1 | |
| SCHEMBL20240298 | 0.67 | LMNA (0.55) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL29960461 | 0.67 | LMNA (0.55) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL28734846 | 0.66 | ALDH1A1 (0.56) | MAPTLMNANPC1RAB9AHPGD | |
| SCHEMBL29507722 | 0.66 | ALDH1A1 (0.56) | MAPTLMNANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |