Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 7/20 | 0.45 |
| ▸ | MMP3 | P08254 | 5/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.45 |
| ▸ | ADAM9 | Q13443 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AREG | P15514 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30518304 | 0.85 | MMP9 (0.46) | MEN1GAAMAPTKMT2AMMP9 | |
| SCHEMBL10037305 | 0.76 | ACE (0.50) | CHEK1JAK2POLBTDP1L3MBTL1 | |
| SCHEMBL10037303 | 0.76 | ACE (0.50) | CHEK1JAK2POLBTDP1L3MBTL1 | |
| SCHEMBL4118662 | 0.75 | MEN1 (0.66) | CHEK1JAK2MEN1GAAMAPT | |
| SCHEMBL8383957 | 0.75 | MEN1 (0.66) | CHEK1JAK2MEN1GAAMAPT | |
| SCHEMBL6920302 | 0.74 | HDAC8 (0.53) | CHEK1JAK2MEN1GAAMAPT | |
| SCHEMBL13856619 | 0.73 | POLB (0.72) | MAPTMMP3POLBTDP1L3MBTL1 | |
| SCHEMBL5098064 | 0.73 | POLB (0.72) | MAPTMMP3POLBTDP1L3MBTL1 | |
| SCHEMBL31685843 | 0.73 | POLB (0.72) | MAPTMMP3POLBTDP1L3MBTL1 | |
| SCHEMBL8383233 | 0.73 | POLB (0.72) | MAPTMMP3POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041972-A1 | CONJUGATES FOR IMMUNOTHERAPY | UNIVERSITY OF SOUTH FLORIDA | 2024-02-08 | — | — | US | claimed |
| US-20240041972-A1 | CONJUGATES FOR IMMUNOTHERAPY | UNIVERSITY OF SOUTH FLORIDA | 2024-02-08 | — | — | US | disclosed |
| US-20230158016-A1 | DELTA OPIOID RECEPTOR ANTAGONISTS REPROGRAM IMMUNOSUPPRESSIVE MICROENVIRONMENT TO BOOST IMMUNOTHERAPY | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158016-A1 | DELTA OPIOID RECEPTOR ANTAGONISTS REPROGRAM IMMUNOSUPPRESSIVE MICROENVIRONMENT TO BOOST IMMUNOTHERAPY | OPRD1, OPRM1, OPRK1 | CHEK1 4012/4885JAK2 281/4885MEN1 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.