Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | ADAM9 | Q13443 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920539 | 0.89 | HTR1A (0.50) | HDAC8SIGMAR1OPRM1MMP9MMP1 | |
| SCHEMBL7533950 | 0.87 | KDM4E (0.50) | HDAC8CHEK1JAK2SIGMAR1OPRM1 | |
| SCHEMBL7533954 | 0.87 | KDM4E (0.50) | HDAC8CHEK1JAK2SIGMAR1OPRM1 | |
| SCHEMBL29870443 | 0.87 | ACE (0.49) | TDP1L3MBTL1CHEK1JAK2POLB | |
| SCHEMBL8336724 | 0.87 | ACE (0.49) | TDP1L3MBTL1CHEK1JAK2POLB | |
| SCHEMBL7478005 | 0.87 | ACE (0.49) | TDP1L3MBTL1CHEK1JAK2POLB | |
| SCHEMBL6820388 | 0.86 | HDAC8 (0.48) | HDAC8MMP9MMP1MMP3ADAM17 | |
| SCHEMBL8342126 | 0.84 | MMP8 (0.58) | TDP1L3MBTL1POLBMMP3 | |
| SCHEMBL8342131 | 0.84 | MMP8 (0.58) | TDP1L3MBTL1POLBMMP3 | |
| SCHEMBL7482104 | 0.80 | HDAC8 (0.54) | HDAC8OPRM1MMP3MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041816-A1 | AZACYCLIC COMPOUNDS AS OREXIN RECEPTOR ANTAGONIST | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |