Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23319934 | 1.00 | DRD1 (0.50) | DRD1RXRARXRBFFAR4FFAR1 | |
| SCHEMBL24154489 | 1.00 | DRD1 (0.50) | DRD1RXRARXRBFFAR4FFAR1 | |
| SCHEMBL25464898 | 0.91 | RXRA (0.40) | DRD1RXRARXRBFFAR4FFAR1 | |
| SCHEMBL25464983 | 0.91 | RXRA (0.45) | DRD1RXRARXRBFFAR4FFAR1 | |
| SCHEMBL21312605 | 0.91 | DRD1 (0.43) | DRD1PRKAG1PRKAA1PRKAB1MRGPRX4 | |
| SCHEMBL24154823 | 0.91 | DRD1 (0.43) | DRD1PRKAG1PRKAA1PRKAB1MRGPRX4 | |
| SCHEMBL23319901 | 0.87 | MAP4K4 (0.39) | DRD1KCNH2THRATHRBMRGPRX4 | |
| SCHEMBL21312464 | 0.87 | ALDH1A1 (0.40) | DRD1MRGPRX4HAO1 | |
| SCHEMBL21296929 | 0.86 | PIN1 (0.49) | FFAR4FFAR1MCL1DHODHPRKAG1 | |
| SCHEMBL21296859 | 0.85 | HAO1 (0.44) | RXRARXRBFFAR4FFAR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | PHOENIX TISSUE REPAIR, INC. | 2023-05-11 | — | — | US | disclosed |
| US-11401246-B2 | Triazole glycolate oxidase inhibitors | Cantero Therapeutics, Inc. (US) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401246-B2 | Triazole glycolate oxidase inhibitors | XDH, DUOX1, PNPO | DRD1 3113/4885RXRA 3619/4885RXRB 3335/4885 |
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | XDH, DUOX1, PNPO | DRD1 3113/4885RXRA 3619/4885RXRB 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.