Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968268 | 0.85 | KDM4E (0.43) | PPARGPIK3C2BMAPK1ALOX5APALDH1A1 | |
| SCHEMBL29967780 | 0.82 | PPARG (0.45) | PPARGPIK3C2BALDH1A1 | |
| SCHEMBL29968433 | 0.82 | CYP19A1 (0.39) | PPARGPIK3C2BCNR2 | |
| SCHEMBL29968198 | 0.79 | DCTPP1 (0.42) | PPARGGALR3NR2F2RAB9A | |
| SCHEMBL29968232 | 0.79 | PDE10A (0.40) | PPARGGALR3NR2F2RAB9A | |
| SCHEMBL29968438 | 0.78 | TSHR (0.37) | PPARGALDH1A1NPSR1CNR2LMNA | |
| SCHEMBL29968901 | 0.77 | DCTPP1 (0.53) | MAPK1ALDH1A1NPSR1CNR2LMNA | |
| SCHEMBL29967688 | 0.77 | CNR2 (0.38) | PPARGCNR2 | |
| SCHEMBL29967971 | 0.76 | PPARG (0.42) | PPARG | |
| SCHEMBL29968012 | 0.76 | NR1H4 (0.46) | PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |