Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967497 | 0.92 | PPARG (0.42) | PPARGKDM4EALDH1A1FABP4ACMSD | |
| SCHEMBL29968433 | 0.89 | CYP19A1 (0.39) | PPARGPIK3C2BAGTR1AGTR2 | |
| SCHEMBL29968268 | 0.86 | KDM4E (0.43) | PPARGPIK3C2BKDM4EALDH1A1ACMSD | |
| SCHEMBL29968012 | 0.85 | NR1H4 (0.46) | PPARGKDM4EALDH1A1AGTR1AGTR2 | |
| SCHEMBL29967688 | 0.84 | CNR2 (0.38) | PPARGKDM4EACMSD | |
| SCHEMBL29967953 | 0.84 | PLA2G10 (0.41) | PPARGFABP4 | |
| SCHEMBL29967971 | 0.83 | PPARG (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968296 | 0.82 | PPARG (0.39) | PPARGPIK3C2BALDH1A1 | |
| SCHEMBL29967767 | 0.81 | FABP4 (0.37) | PPARGKDM4EALDH1A1FABP4ACMSD | |
| SCHEMBL29968198 | 0.80 | DCTPP1 (0.42) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |