SCHEMBL29968339

SCHEMBL29968339

COc1ccc(CC(C)N)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.75
HTR1A P08908 1/20 0.59
HTR2C P28335 1/20 0.59
HTR2B P41595 1/20 0.59
TAAR1 Q96RJ0 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL266899 1.00 HTR2A (0.75) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL2556418 1.00 HTR2A (0.75) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL1740902 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL31545209 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL1740903 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL3460220 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL3027061 0.85 APLNR (0.59) HTR2A
Hydrochloric Acid SCHEMBL29542459 0.84 HTR2A (0.97) HTR2AHTR1AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL3486527 0.84 HTR2A (0.97) HTR2AHTR1AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL30861235 0.84 HTR2A (0.97) HTR2AHTR1AHTR2CHTR2BTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4061359-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH Turtle Bear Holdings, LLC (US) 2022-09-28 EP claimed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
EP-4618981-A1 COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE Remedi, Inc. (US) 2025-09-24 EP disclosed
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 US disclosed
WO-2025024400-A2 SUBSTITUTED TRYPTAMINES AND USES THEREOF 2A BIOSCIENCES, INC. (US) 2025-01-30 WO disclosed
WO-2024251807-A1 COMPANION ANIMAL TREATMENTS CYBIN IRL LIMITED (IE) 2024-12-12 WO disclosed
WO-2024243599-A1 ASYMMETRIC PHENYLALKYLAMINES ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) 2024-11-28 WO disclosed
EP-4452986-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-10-30 EP disclosed
WO-2024178425-A1 HYDROXYALKYL AND METHOXYALKYL TRYPTAMINES 2A BIOSCIENCES, INC. (US) 2024-08-29 WO disclosed
CN-118234491-A Hallucinogen-fatty acid combinations 明德赛特制药公司 2024-06-21 CN disclosed
WO-2024108195-A1 COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE REMEDI, INC. (US) 2024-05-23 WO disclosed
WO-2024091523-A1 CONFORMATIONALLY RESTRICTED PHENETHYLAMINE ANALOGS 2A BIOSCIENCES, INC. (US) 2024-05-02 WO disclosed
CN-117715632-A Compositions comprising an enzyme-cleavable prodrug and nafamostat and methods of use thereof 恩赛斯生物科学股份有限公司 2024-03-15 CN disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 WO disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 WO disclosed
EP-4061359-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH Turtle Bear Holdings, LLC (US) 2022-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A HTR2A 8/4885HTR1A 3/4885HTR2C 2/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A HTR2A 8/4885HTR1A 3/4885HTR2C 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.