SCHEMBL266899

SCHEMBL266899

COc1ccc(CC(C)N)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.75
HTR1A P08908 1/20 0.59
HTR2C P28335 1/20 0.59
HTR2B P41595 1/20 0.59
TAAR1 Q96RJ0 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29968339 1.00 HTR2A (0.75) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL2556418 1.00 HTR2A (0.75) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL1740902 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL31545209 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL1740903 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL3460220 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BTAAR1
SCHEMBL3027061 0.85 APLNR (0.59) HTR2A
Hydrochloric Acid SCHEMBL29542459 0.84 HTR2A (0.97) HTR2AHTR1AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL3486527 0.84 HTR2A (0.97) HTR2AHTR1AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL30861235 0.84 HTR2A (0.97) HTR2AHTR1AHTR2CHTR2BTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
WO-2021101926-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH STAMETS PAUL EDWARD (US) 2021-05-27 WO claimed
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-05-20 US claimed
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-03-11 US claimed
US-20160000815-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CT HOLDINGS PTY LTD (AU) 2016-01-07 US claimed
EP-2729216-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2014-05-14 EP claimed
WO-2013007698-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2013-01-17 WO claimed
JP-2011529923-A 2011-12-15 JP claimed
CN-102170874-A Compositions and methods for treating psychiatric disorders GOSFORTH CT HOLDINGS PTY LTD 2011-08-31 CN claimed
US-20110207718-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD. (AU) 2011-08-25 US claimed
EP-2331088-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2011-06-15 EP claimed
US-20100172916-A1 SUBSTITUTED HYDROXYPHENYLAMINE COMPOUNDS AUSPEX PHARMACEUTICALS, INC. (US) 2010-07-08 US claimed
WO-2010054286-A2 SUBSTITUTED HYDROXYPHENYLAMINE COMPOUNDS AUSPEX PHARMACEUTICALS, INC. (US) 2010-05-14 WO claimed
WO-2010015029-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2010-02-11 WO claimed
US-7550375-B2 Method for forming metal bumps ADVANCED SEMICONDUCTOR ENGINEERING INC. (TW) 2009-06-23 US claimed
US-20070218676-A1 Method for forming metal bumps ADVANCED SEMICONDUCTOR ENGINEERING INC. (TW) 2007-09-20 US claimed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
CN-86106226-A 20-and 21-amino steroids 1987-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 11/4885HTR1A 13/4885HTR2C 6/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A HTR2A 14/4885HTR1A 9/4885HTR2C 42/4885
US-20100172916-A1 SUBSTITUTED HYDROXYPHENYLAMINE COMPOUNDS MC1R, TYR, MITF HTR2A 62/4885HTR1A 99/4885HTR2C 84/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B HTR2A 19/4885HTR1A 22/4885HTR2C 12/4885
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 11/4885HTR1A 13/4885HTR2C 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.