Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288534 | 0.79 | KDM4E (0.86) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289139 | 0.79 | KDM4E (0.86) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL288491 | 0.79 | CDC7 (0.60) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL14582053 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL5759200 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL2162886 | 0.77 | KDM4E (0.58) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL2179717 | 0.74 | TRPM8 (0.58) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL298601 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4EKMT2ARAB9AGAA | |
| SCHEMBL17212202 | 0.73 | CDC7 (0.62) | ALDH1A1KDM4EKMT2AGAAHPGD | |
| SCHEMBL289682 | 0.73 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2ARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |